IN SILICO STUDY OF ACRYLAMIDE TOXICITIES USING TOXTREE METHOD AND ITS ANALYSIS IN POTATO CHIPS USING HPLC METHOD

Abstract

Acrylamide is among the contaminants commonly
present in the food due to processing. Acrylamide is
classified as a hazardous material which has potency
as human’s body carcinogenic for the case of cancer
about 2% per year in the world. Acrylamide was
found in food processed by the high temperature
(above 120ºC) in food with high carbohydrates
contents, such as potato chips.
Figure 1. The chemical structure of acylamide
OBJECTIVES
The aim of this research was to obtain:
- the toxicities of acrylamide and the functional
groups or moieties responsible for those
toxicities using Toxtree software.
- analysis of acrylamide in potato chips using HPLC
(High Performance Liquid Chromatography)
method.